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Destabilization of the Dystrophin-Glycoprotein Complex without Functional Deficits in α-Dystrobrevin Null Muscle

α-Dystrobrevin is a component of the dystrophin-glycoprotein complex (DGC) and is thought to have both structural and signaling roles in skeletal muscle. Mice deficient for α-dystrobrevin (adbn(−/−)) exhibit extensive myofiber degeneration and neuromuscular junction abnormalities. However, the bioch...

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Detalhes bibliográficos
Main Authors: Bunnell, Tina M., Jaeger, Michele A., Fitzsimons, Daniel P., Prins, Kurt W., Ervasti, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2432020/
https://ncbi.nlm.nih.gov/pubmed/18596960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002604
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