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Dystrobrevin increases dystrophin's binding to the dystrophin-glycoprotein complex and provides protection during cardiac stress

Duchenne muscular dystrophy is a fatal progressive disease of both cardiac and skeletal muscle resulting from the mutations in the DMD gene and loss of the protein dystrophin. Alpha-dystrobrevin (α-DB) tightly associates with dystrophin but significance of this interaction within cardiac myocytes is...

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Detalles Bibliográficos
Publicado en:J Mol Cell Cardiol
Autores principales: Strakova, Jana, Dean, John D., Sharpe, Katharine, Meyers, Tatyana A., Odom, Guy, Townsend, DeWayne
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271192/
https://ncbi.nlm.nih.gov/pubmed/25158611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.08.013
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