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Context-dependent functional substitution of α-skeletal actin by γ-cytoplasmic actin

We generated transgenic mice that overexpressed γ-(cyto) actin 2000-fold above wild-type levels in skeletal muscle. γ-(cyto) actin comprised 40% of total actin in transgenic skeletal muscle, with a concomitant 40% decrease in α-actin. Surprisingly, transgenic muscle was histologically and ultrastruc...

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Bibliografiset tiedot
Päätekijät: Jaeger, Michele A., Sonnemann, Kevin J., Fitzsimons, Daniel P., Prins, Kurt W., Ervasti, James M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Federation of American Societies for Experimental Biology 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704599/
https://ncbi.nlm.nih.gov/pubmed/19279140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-129783
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