Evidence suggesting the presence of a stem cell clone anteceding the acquisition of the JAK2-V617F mutation

Eitemau Tebyg

• Telomere length is severely and similarly reduced in JAK2V617F-positive and -negative myeloproliferative neoplasms
  gan: Bernard, L, et al.
  Cyhoeddwyd: (2008)
• X-inactivation–based clonality analysis and quantitative JAK2V617F assessment reveal a strong association between clonality and JAK2V617F in PV but not ET/MMM, and identifies a subset of JAK2V617F-negative ET and MMM patients with clonal hematopoiesis
  gan: Levine, Ross L., et al.
  Cyhoeddwyd: (2006)
• JAK2V617F: you can't have too much
  gan: Levine, Ross L.
  Cyhoeddwyd: (2008)
• JAK2 V617F negative essential thrombocythemia
  gan: Kashif, A.W., et al.
  Cyhoeddwyd: (2012)
• JAK2(V617F)-mutant Vascular Niche Contributes to JAK2(V617F) Clonal Expansion in Myeloproliferative Neoplasms
  gan: Lin, Chi Hua Sarah, et al.
  Cyhoeddwyd: (2016)