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Telomere length is severely and similarly reduced in JAK2V617F-positive and -negative myeloproliferative neoplasms

Myeloproliferative neoplasms (MPNs) are clonal stem cell disorders characterized by chronic proliferation of hematopoietic progenitors. We studied the telomere length (TL) of 335 MPN patients and 93 gender- and age-matched controls using a quantitative PCR method (relative TL calculated as the ratio...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Bernard, L, Belisle, C, Mollica, L, Provost, S, Roy, D-C, Gilliland, DG, Levine, RL, Busque, L
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640467/
https://ncbi.nlm.nih.gov/pubmed/19005480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2008.319
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