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Cdc42-dependent actin dynamics controls maturation and secretory activity of dendritic cells

Cell division cycle 42 (Cdc42) is a member of the Rho guanosine triphosphatase family and has pivotal functions in actin organization, cell migration, and proliferation. To further study the molecular mechanisms of dendritic cell (DC) regulation by Cdc42, we used Cdc42-deficient DCs. Cdc42 deficienc...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Schulz, Anna M., Stutte, Susanne, Hogl, Sebastian, Luckashenak, Nancy, Dudziak, Diana, Leroy, Céline, Forné, Ignasi, Imhof, Axel, Müller, Stephan A., Brakebusch, Cord H., Lichtenthaler, Stefan F., Brocker, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639873/
https://ncbi.nlm.nih.gov/pubmed/26553928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201503128
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