Wordt geladen...
Structural insights into μ-opioid receptor activation
Activation of the μ-opioid receptor (μOR) is responsible for the efficacy of the most effective analgesics. To understand the structural basis for μOR activation, we obtained a 2.1 Å X-ray crystal structure of the μOR bound to the morphinan agonist BU72 and stabilized by a G protein-mimetic camelid-...
Bewaard in:
| Gepubliceerd in: | Nature |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4639397/ https://ncbi.nlm.nih.gov/pubmed/26245379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14886 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|