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Propagation of conformational changes during μ-opioid receptor activation
μ-Opioid receptors (μOR) are G protein coupled receptors (GPCRs) that are activated by a structurally diverse spectrum of natural and synthetic agonists including endogenous endorphin peptides, morphine and methadone. The recent structures of the μOR in inactive(1) and agonist-induced active states...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4820006/ https://ncbi.nlm.nih.gov/pubmed/26245377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14680 |
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