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HIV-1 Nef hijacks clathrin coats by stabilizing AP-1:Arf1 polygons
The lentiviruses HIV and SIV subvert intracellular membrane traffic as part of their replication cycle. The lentiviral Nef protein helps viruses evade innate and adaptive immune defenses by hijacking the AP-1 and -2 clathrin adaptors. Here we found that HIV-1 Nef and the GTPase Arf1 induced trimeriz...
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| Publicado no: | Science |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4638387/ https://ncbi.nlm.nih.gov/pubmed/26494761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aac5137 |
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