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Microhomology-mediated end joining: a back-up survival mechanism or dedicated pathway?
DNA double-strand breaks (DSBs) disrupt the continuity of chromosomes and their repair by error-free mechanisms is essential to preserve genome integrity. Microhomology-mediated end joining (MMEJ) is an error-prone repair mechanism that involves alignment of microhomologous sequences internal to the...
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| Publicado no: | Trends Biochem Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4638128/ https://ncbi.nlm.nih.gov/pubmed/26439531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2015.08.006 |
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