Blockade of B-cell activating factor with TACI-IgG effectively reduced Th1 and Th17 cells but not memory T cells in experimental allergic encephalomyelitis mice

B-cell activating factor (BAFF) is regarded as a new therapeutic target in autoimmune diseases such as systemic lupus erythematosus (SLE) and multiple sclerosis (MS). Along with other researchers, we have demonstrated that BAFF inhibitor atacicept (TACI-IgG) suppresses lupus and experimental allergi...

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Detalhes bibliográficos
Publicado no:Cent Eur J Immunol
Main Authors: Wang, Xiaoqian, Xiao, He, Wei, Yinxiang, Liu, Xiaoling, Han, Gencheng, Chen, Guojiang, Hou, Chunmei, Shen, Beifen, Li, Yan, Wang, Renxi
Formato: Artigo
Idioma:Inglês
Publicado em: Polish Society of Experimental and Clinical Immunology 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637387/
https://ncbi.nlm.nih.gov/pubmed/26557026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/ceji.2015.52826
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