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Lipopolysaccharide regulation of intestinal tight junction permeability is mediated by TLR-4 signal transduction pathway activation of FAK and MyD88
Gut-derived bacterial lipopolysaccharides (LPS) play an essential role in inducing intestinal and systemic inflammatory responses and have been implicated as a pathogenic factor of necrotizing enterocolitis (NEC) and inflammatory bowel disease (IBD). The defective intestinal tight junction (TJ) barr...
Enregistré dans:
Publié dans: | J Immunol |
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Auteurs principaux: | , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
2015
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4637237/ https://ncbi.nlm.nih.gov/pubmed/26466961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402598 |
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