Lipopolysaccharide-Induced Increase in Intestinal Epithelial Tight Permeability Is Mediated by Toll-Like Receptor 4/Myeloid Differentiation Primary Response 88 (MyD88) Activation of Myosin Light Chain Kinase Expression

Lipopolysaccharides (LPSs) are a major component of the Gram-negative bacterial cell wall and play an important role in mediating intestinal inflammatory responses in inflammatory bowel disease. Although recent studies suggested that physiologically relevant concentrations of LPS (0 to 1 ng/mL) caus...

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Publicado en:Am J Pathol
Main Authors: Nighot, Meghali, Al-Sadi, Rana, Guo, Shuhong, Rawat, Manmeet, Nighot, Prashant, Watterson, Martin D., Ma, Thomas Y.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718096/
https://ncbi.nlm.nih.gov/pubmed/29157665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.08.005
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