TLR4/MyD88 -mediated CCL2 production by lipopolysaccharide (endotoxin): Implications for metabolic inflammation

BACKGROUND: Obese human and mice were reported to have higher circularity endotoxin (LPS) levels as compared to their lean counter parts. The current study was aimed to reveal the molecular mechanisms underlying the LPS mediated induction of CCL2 in human monocytes/macrophages. METHODS: Human monocy...

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Detalhes bibliográficos
Publicado no:J Diabetes Metab Disord
Main Authors: Akhter, Nadeem, Hasan, Amal, Shenouda, Steve, Wilson, Ajit, Kochumon, Shihab, Ali, Shamsha, Tuomilehto, Jaakko, Sindhu, Sardar, Ahmad, Rasheed
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154519/
https://ncbi.nlm.nih.gov/pubmed/30288388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40200-018-0341-y
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