TLR4/MyD88 -mediated CCL2 production by lipopolysaccharide (endotoxin): Implications for metabolic inflammation

BACKGROUND: Obese human and mice were reported to have higher circularity endotoxin (LPS) levels as compared to their lean counter parts. The current study was aimed to reveal the molecular mechanisms underlying the LPS mediated induction of CCL2 in human monocytes/macrophages. METHODS: Human monocy...

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Bibliographic Details
Published in:J Diabetes Metab Disord
Main Authors: Akhter, Nadeem, Hasan, Amal, Shenouda, Steve, Wilson, Ajit, Kochumon, Shihab, Ali, Shamsha, Tuomilehto, Jaakko, Sindhu, Sardar, Ahmad, Rasheed
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154519/
https://ncbi.nlm.nih.gov/pubmed/30288388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40200-018-0341-y
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