TLR4/MyD88 -mediated CCL2 production by lipopolysaccharide (endotoxin): Implications for metabolic inflammation

BACKGROUND: Obese human and mice were reported to have higher circularity endotoxin (LPS) levels as compared to their lean counter parts. The current study was aimed to reveal the molecular mechanisms underlying the LPS mediated induction of CCL2 in human monocytes/macrophages. METHODS: Human monocy...

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Publicado en:J Diabetes Metab Disord
Main Authors: Akhter, Nadeem, Hasan, Amal, Shenouda, Steve, Wilson, Ajit, Kochumon, Shihab, Ali, Shamsha, Tuomilehto, Jaakko, Sindhu, Sardar, Ahmad, Rasheed
Formato: Artigo
Idioma:Inglês
Publicado: Springer International Publishing 2018
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154519/
https://ncbi.nlm.nih.gov/pubmed/30288388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40200-018-0341-y
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