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The Effects of Lipid Membranes, Crowding and Osmolytes on the Aggregation, and Fibrillation Propensity of Human IAPP

Type 2 diabetes mellitus (T2DM) is an age-related and metabolic disease. Its development is hallmarked, among others, by the dysfunction and degeneration of β-cells of the pancreatic islets of Langerhans. The major pathological characteristic thereby is the formation of extracellular amyloid deposit...

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Podrobná bibliografie
Vydáno v:J Diabetes Res
Hlavní autoři: Gao, Mimi, Winter, Roland
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637101/
https://ncbi.nlm.nih.gov/pubmed/26582333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/849017
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