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Macromolecular Crowding as a Suppressor of Human IAPP Fibril Formation and Cytotoxicity
The biological cell is known to exhibit a highly crowded milieu, which significantly influences protein aggregation and association processes. As several cell degenerative diseases are related to the self-association and fibrillation of amyloidogenic peptides, understanding of the impact of macromol...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726762/ https://ncbi.nlm.nih.gov/pubmed/23922768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069652 |
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