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The effect of Aβ on IAPP aggregation in the presence of an isolated β-cell membrane
Fibrillar aggregates of the islet amyloid polypeptide (IAPP) and amyloid-β (Aβ) are known to deposit at pancreatic β-cells and neuronal cells, and are associated with the cell degenerative diseases type-2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), respectively. Since IAPP is secrete...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4075326/ https://ncbi.nlm.nih.gov/pubmed/22321797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.01.048 |
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