Interacting partners of macrophage-secreted cathepsin B contribute to HIV-induced neuronal apoptosis

OBJECTIVE: HIV-1 infection of macrophages increases cathepsin B secretion and induces neuronal apoptosis, but the molecular mechanism remains unclear. DESIGN: We identified macrophage secreted cathepsin B protein interactions extracellularly and their contribution to neuronal death in vitro. METHODS...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:AIDS
Egile Nagusiak: CANTRES-ROSARIO, Yisel M., HERNANDEZ, Natalia, NEGRON, Karla, PEREZ-LASPIUR, Juliana, LESZYK, John, SHAFFER, Scott A., MELENDEZ, Loyda M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636939/
https://ncbi.nlm.nih.gov/pubmed/26208400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000000823
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