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Dimethyl fumarate prevents HIV-induced lysosomal dysfunction and cathepsin B release from macrophages
HIV-associated neurocognitive disorders (HAND) are prevalent despite combined antiretroviral therapy, affecting nearly half of HIV-infected patients worldwide. During HIV infection of macrophages secretion of the lysosomal protein, cathepsin B, is increased. Secreted cathepsin B has been shown to in...
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| 出版年: | J Neuroimmune Pharmacol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6503672/ https://ncbi.nlm.nih.gov/pubmed/29987592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-018-9794-5 |
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