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Dimethyl fumarate prevents HIV-induced lysosomal dysfunction and cathepsin B release from macrophages

HIV-associated neurocognitive disorders (HAND) are prevalent despite combined antiretroviral therapy, affecting nearly half of HIV-infected patients worldwide. During HIV infection of macrophages secretion of the lysosomal protein, cathepsin B, is increased. Secreted cathepsin B has been shown to in...

詳細記述

保存先:
書誌詳細
出版年:J Neuroimmune Pharmacol
主要な著者: Rosario, Lester, Colón, Krystal, Borges, Gabriel, Negrón, Karla, Meléndez, Loyda M.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503672/
https://ncbi.nlm.nih.gov/pubmed/29987592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-018-9794-5
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