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53BP1 and the LINC complex promote microtubule-dependent DSB mobility and DNA repair
Increased mobility of chromatin surrounding Double Strand Breaks (DSBs) has been noted in yeast and mammalian cells but how it is driven and whether it contributes to DSB repair remain unclear. Here, we use a telomere-based system to track DNA damage foci with high resolution in living cells. We fin...
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| Veröffentlicht in: | Cell |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4636737/ https://ncbi.nlm.nih.gov/pubmed/26544937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.09.057 |
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