Llwytho...

53BP1 and the LINC complex promote microtubule-dependent DSB mobility and DNA repair

Increased mobility of chromatin surrounding Double Strand Breaks (DSBs) has been noted in yeast and mammalian cells but how it is driven and whether it contributes to DSB repair remain unclear. Here, we use a telomere-based system to track DNA damage foci with high resolution in living cells. We fin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell
Prif Awduron: Lottersberger, Francisca, Karssemeijer, Roos Anna, Dimitrova, Nadya, de Lange, Titia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636737/
https://ncbi.nlm.nih.gov/pubmed/26544937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.09.057
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