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Delivering on the promise: PARP inhibition as targeted anti-cancer therapy
PURPOSE OF THE REVIEW: Authors present the rationale, clinical development, and current status of Poly (adenosine diphospohate [ADP]) ribose polymerase (PARP) inhibitors (PARPi) as anticancer agents. RECENT FINDINGS: The recent approval of olaparib in heavily pre-treated patients with advanced ovari...
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| Publicado en: | Curr Opin Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4636335/ https://ncbi.nlm.nih.gov/pubmed/26447876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCO.0000000000000238 |
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