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Wee1 kinase as a target for cancer therapy
Wee1, a protein kinase, regulates the G(2) checkpoint in response to DNA damage. Preclinical studies have elucidated the role of wee1 in DNA damage repair and the stabilization of replication forks, supporting the validity of wee1 inhibition as a viable therapeutic target in cancer. MK-1775, a selec...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3865011/ https://ncbi.nlm.nih.gov/pubmed/24013427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26062 |
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