Activation of AMP-Activated Protein Kinase by Adenine Alleviates TNF-Alpha-Induced Inflammation in Human Umbilical Vein Endothelial Cells

The AMP-activated protein kinase (AMPK) signaling system plays a key role in cellular stress by repressing the inflammatory responses induced by the nuclear factor-kappa B (NF-κB) system. Previous studies suggest that the anti-inflammatory role of AMPK involves activation by adenine, but the mechani...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cheng, Yi-Fang, Young, Guang-Huar, Lin, Jiun-Tsai, Jang, Hyun-Hwa, Chen, Chin-Chen, Nong, Jing-Yi, Chen, Po-Ku, Kuo, Cheng-Yi, Kao, Shao-Hsuan, Liang, Yao-Jen, Chen, Han-Min
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636334/
https://ncbi.nlm.nih.gov/pubmed/26544976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142283
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