Adenine causes cell cycle arrest and autophagy of chronic myelogenous leukemia K562 cells via AMP-activated protein kinase signaling

AMP-activated protein kinase (AMPK) is known as a pivotal regulator of cellular metabolism. Mounting evidences have demonstrated that AMPK activation exerts tumor suppressive activity on leukemia cells. The present study reported that adenine, an AMPK activator, triggers cell cycle arrest and autoph...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Chen, San-Yuan, Lin, Chun-Hsiang, Lin, Jiun-Tsai, Cheng, Yi-Fang, Chen, Han-Min, Kao, Shao-Hsuan
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656030/
https://ncbi.nlm.nih.gov/pubmed/29113185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6890
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados