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Adenine inhibits growth of hepatocellular carcinoma cells via AMPK-mediated S phase arrest and apoptotic cascade

Background: Adenine exhibits potential anticancer activity against several types of malignancies. However, whether adenine has anticancer effects on hepatocellular carcinoma (HCC) cells is incompletely explored. Methods: Human HCC cell lines HepG2 and SK-Hep-1 (p53-wild type) and Hep3B (p53-deficien...

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Detalhes bibliográficos
Publicado no:Int J Med Sci
Main Authors: Su, Wei-Wen, Huang, Jen-Yu, Chen, Han-Min, Lin, Jiun-Tsai, Kao, Shao-Hsuan
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085215/
https://ncbi.nlm.nih.gov/pubmed/32210718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.42086
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