Adenine alleviates iron overload by cAMP/PKA mediated hepatic hepcidin in mice

Hemochromatosis is prevalent and often associated with high rates of morbidity and mortality worldwide. The safe alternative iron-reducing approaches are urgently needed in order to better control iron overload. Our unbiased vitamin screen for modulators of hepcidin, a master iron regulatory hormone...

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Veröffentlicht in:J Cell Physiol
Hauptverfasser: Zhang, Yingqi, Wang, Xudong, Wu, Qian, Wang, Hao, Zhao, Lu, Wang, Xinhui, Mu, Mingdao, Xie, Enjun, He, Xuyan, Shao, Dandan, Shang, Yanna, Lai, Yongrong, Ginzburg, Yelena, Min, Junxia, Wang, Fudi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754534/
https://ncbi.nlm.nih.gov/pubmed/29600572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.26559
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