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IRF4-Dependent and IRF4-Independent Pathways Contribute to DC Dysfunction in Lupus

Interferon Regulatory Factors (IRFs) play fundamental roles in dendritic cell (DC) differentiation and function. In particular, IRFs are critical transducers of TLR signaling and dysregulation in this family of factors is associated with the development of autoimmune disorders such as Systemic Lupus...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Manni, Michela, Gupta, Sanjay, Nixon, Briana G., Weaver, Casey T., Jessberger, Rolf, Pernis, Alessandra B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636285/
https://ncbi.nlm.nih.gov/pubmed/26544714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141927
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