Synergistic killing of NDM-producing MDR Klebsiella pneumoniae by two ‘old’ antibiotics—polymyxin B and chloramphenicol

OBJECTIVES: Combination therapy is an important option in the fight against Gram-negative ‘superbugs’. This study systematically investigated bacterial killing and the emergence of polymyxin resistance with polymyxin B and chloramphenicol combinations used against New Delhi metallo-β-lactamase (NDM)...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Abdul Rahim, Nusaibah, Cheah, Soon-Ee, Johnson, Matthew D., Yu, Heidi, Sidjabat, Hanna E., Boyce, John, Butler, Mark S., Cooper, Matthew A., Fu, Jing, Paterson, David L., Nation, Roger L., Bergen, Phillip J., Velkov, Tony, Li, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635649/
https://ncbi.nlm.nih.gov/pubmed/26023209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkv135
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