Synergistic killing of NDM-producing MDR Klebsiella pneumoniae by two ‘old’ antibiotics—polymyxin B and chloramphenicol

OBJECTIVES: Combination therapy is an important option in the fight against Gram-negative ‘superbugs’. This study systematically investigated bacterial killing and the emergence of polymyxin resistance with polymyxin B and chloramphenicol combinations used against New Delhi metallo-β-lactamase (NDM)...

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Bibliografische gegevens
Gepubliceerd in:J Antimicrob Chemother
Hoofdauteurs: Abdul Rahim, Nusaibah, Cheah, Soon-Ee, Johnson, Matthew D., Yu, Heidi, Sidjabat, Hanna E., Boyce, John, Butler, Mark S., Cooper, Matthew A., Fu, Jing, Paterson, David L., Nation, Roger L., Bergen, Phillip J., Velkov, Tony, Li, Jian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2015
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635649/
https://ncbi.nlm.nih.gov/pubmed/26023209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkv135
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