Novel Polymyxin Combination with the Antiretroviral Zidovudine Exerts Synergistic Killing against NDM-Producing Multidrug-Resistant Klebsiella pneumoniae

Polymyxins are used as a last-line therapy against multidrug-resistant (MDR) New Delhi metallo-β-lactamase (NDM)-producing Klebsiella pneumoniae. However, polymyxin resistance can emerge with monotherapy; therefore, novel strategies are urgently needed to minimize the resistance and maintain their c...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Lin, Yu-Wei, Abdul Rahim, Nusaibah, Zhao, Jinxin, Han, Mei-Ling, Yu, Heidi H., Wickremasinghe, Hasini, Chen, Ke, Wang, Jiping, Paterson, David L., Zhu, Yan, Rao, Gauri G., Zhou, Qi Tony, Forrest, Alan, Velkov, Tony, Li, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437486/
https://ncbi.nlm.nih.gov/pubmed/30670431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02176-18
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