Synergistic killing of NDM-producing MDR Klebsiella pneumoniae by two ‘old’ antibiotics—polymyxin B and chloramphenicol

OBJECTIVES: Combination therapy is an important option in the fight against Gram-negative ‘superbugs’. This study systematically investigated bacterial killing and the emergence of polymyxin resistance with polymyxin B and chloramphenicol combinations used against New Delhi metallo-β-lactamase (NDM)...

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Dades bibliogràfiques
Publicat a:J Antimicrob Chemother
Autors principals: Abdul Rahim, Nusaibah, Cheah, Soon-Ee, Johnson, Matthew D., Yu, Heidi, Sidjabat, Hanna E., Boyce, John, Butler, Mark S., Cooper, Matthew A., Fu, Jing, Paterson, David L., Nation, Roger L., Bergen, Phillip J., Velkov, Tony, Li, Jian
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635649/
https://ncbi.nlm.nih.gov/pubmed/26023209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkv135
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