Plecanatide and dolcanatide, novel guanylate cyclase-C agonists, ameliorate gastrointestinal inflammation in experimental models of murine colitis

AIM: To evaluate the effect of orally administered plecanatide or dolcanatide, analogs of uroguanylin, on amelioration of colitis in murine models. METHODS: The cyclic guanosine monophosphate (cGMP) stimulatory potency of plecanatide and dolcanatide was measured using a human colon carcinoma T84 cel...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:World J Gastrointest Pharmacol Ther
Päätekijät: Shailubhai, Kunwar, Palejwala, Vaseem, Arjunan, Krishna Priya, Saykhedkar, Sayali, Nefsky, Bradley, Foss, John A, Comiskey, Stephen, Jacob, Gary S, Plevy, Scott E
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Baishideng Publishing Group Inc 2015
Aiheet:
Basic Study
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635161/
https://ncbi.nlm.nih.gov/pubmed/26558155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4292/wjgpt.v6.i4.213
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia