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ATM, ATR and DNA-PKcs expressions correlate to adverse clinical outcomes in epithelial ovarian cancers

BACKGROUND: Ataxia-telangiectasia mutated (ATM), ataxia-telangiectasia mutated and rad3 related (ATR) and DNA-dependent protein kinase catalytic sub-unit (DNA-PKcs) play critical roles in DNA damage response (DDR) by linking DNA damage sensing to DDR effectors that regulate cell cycle progression an...

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Detalhes bibliográficos
Publicado no:BBA Clin
Main Authors: Abdel-Fatah, Tarek M.A., Arora, Arvind, Moseley, Paul, Coveney, Clare, Perry, Christina, Johnson, Kerstie, Kent, Christopher, Ball, Graham, Chan, Stephen, Madhusudan, Srinivasan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633921/
https://ncbi.nlm.nih.gov/pubmed/26674120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbacli.2014.08.001
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