Targeting HER-3 to elicit antitumor helper T cells against head and neck squamous cell carcinoma

HER-3 expression has been reported to act as an important oncoprotein in head and neck squamous cell carcinoma. This protein is known to control tumor proliferation and acquisition of resistance by tumor cells towards EGFR inhibitors, therefore, development of a HER-3-targeted therapy is desirable....

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Publicado no:Sci Rep
Main Authors: Kumai, Takumi, Ohkuri, Takayuki, Nagato, Toshihiro, Matsuda, Yoshinari, Oikawa, Kensuke, Aoki, Naoko, Kimura, Shoji, Celis, Esteban, Harabuchi, Yasuaki, Kobayashi, Hiroya
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633732/
https://ncbi.nlm.nih.gov/pubmed/26538233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16280
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