Targeting HER-3 to elicit antitumor helper T cells against head and neck squamous cell carcinoma

HER-3 expression has been reported to act as an important oncoprotein in head and neck squamous cell carcinoma. This protein is known to control tumor proliferation and acquisition of resistance by tumor cells towards EGFR inhibitors, therefore, development of a HER-3-targeted therapy is desirable....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Kumai, Takumi, Ohkuri, Takayuki, Nagato, Toshihiro, Matsuda, Yoshinari, Oikawa, Kensuke, Aoki, Naoko, Kimura, Shoji, Celis, Esteban, Harabuchi, Yasuaki, Kobayashi, Hiroya
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633732/
https://ncbi.nlm.nih.gov/pubmed/26538233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16280
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