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HCV Drug Resistance Challenges in Japan: The Role of Pre-Existing Variants and Emerging Resistant Strains in Direct Acting Antiviral Therapy

Sustained virological response (SVR) rates have increased dramatically following the approval of direct acting antiviral (DAA) therapies. While individual DAAs have a low barrier to resistance, most patients can be successfully treated using DAA combination therapy. However, DAAs are vulnerable to d...

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Dettagli Bibliografici
Pubblicato in:Viruses
Autori principali: Chayama, Kazuaki, Hayes, C. Nelson
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632384/
https://ncbi.nlm.nih.gov/pubmed/26473914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7102876
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