Identification of HCV Resistant Variants against Direct Acting Antivirals in Plasma and Liver of Treatment Naïve Patients

Current standard-of-care treatment of chronically infected hepatitis C virus (HCV) patients involves direct-acting antivirals (DAA). However, concerns exist regarding the emergence of drug -resistant variants and subsequent treatment failure. In this study, we investigate potential natural drug-resi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Raj, V. Stalin, Hundie, Gadissa Bedada, Schürch, Anita C., Smits, Saskia L., Pas, Suzan D., Le Pogam, Sophie, Janssen, Harry L. A., de Knegt, Rob J., Osterhaus, Albert D. M. E., Najera, Isabel, Boucher, Charles A., Haagmans, Bart L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498547/
https://ncbi.nlm.nih.gov/pubmed/28680115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04931-y
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