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Global prevalence of pre-existing HCV variants resistant to direct-acting antiviral agents (DAAs): mining the GenBank HCV genome data

Direct-acting antiviral agents (DAAs) against hepatitis C virus (HCV) proteins open a whole new era for anti-HCV therapy, but DAA resistance associated variants (RAVs) could jeopardize the effectiveness of DAAs. We reported the global prevalence of DAA RAVs using published GenBank data. 58.7% of seq...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Chen, Zhi-wei, Li, Hu, Ren, Hong, Hu, Peng
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740856/
https://ncbi.nlm.nih.gov/pubmed/26842909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20310
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