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HCV Drug Resistance Challenges in Japan: The Role of Pre-Existing Variants and Emerging Resistant Strains in Direct Acting Antiviral Therapy

Sustained virological response (SVR) rates have increased dramatically following the approval of direct acting antiviral (DAA) therapies. While individual DAAs have a low barrier to resistance, most patients can be successfully treated using DAA combination therapy. However, DAAs are vulnerable to d...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Chayama, Kazuaki, Hayes, C. Nelson
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632384/
https://ncbi.nlm.nih.gov/pubmed/26473914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7102876
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