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p53 regulates the mevalonate pathway in human glioblastoma multiforme
The mevalonate (MVA) pathway is an important metabolic pathway implicated in multiple aspects of tumorigenesis. In this study, we provided evidence that p53 induces the expression of a group of enzymes of the MVA pathway including 3′-hydroxy-3′-methylglutaryl-coenzyme A reductase, MVA kinase, farnes...
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| Published in: | Cell Death Dis |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4632304/ https://ncbi.nlm.nih.gov/pubmed/26469958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.279 |
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