p53 regulates the mevalonate pathway in human glioblastoma multiforme

The mevalonate (MVA) pathway is an important metabolic pathway implicated in multiple aspects of tumorigenesis. In this study, we provided evidence that p53 induces the expression of a group of enzymes of the MVA pathway including 3′-hydroxy-3′-methylglutaryl-coenzyme A reductase, MVA kinase, farnes...

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Bibliographic Details
Published in:	Cell Death Dis
Main Authors:	Laezza, C, D'Alessandro, A, Di Croce, L, Picardi, P, Ciaglia, E, Pisanti, S, Malfitano, A M, Comegna, M, Faraonio, R, Gazzerro, P, Bifulco, M
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group 2015
Subjects:	Original Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4632304/ https://ncbi.nlm.nih.gov/pubmed/26469958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.279
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p53 regulates the mevalonate pathway in human glioblastoma multiforme

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