p53 regulates the mevalonate pathway in human glioblastoma multiforme

The mevalonate (MVA) pathway is an important metabolic pathway implicated in multiple aspects of tumorigenesis. In this study, we provided evidence that p53 induces the expression of a group of enzymes of the MVA pathway including 3′-hydroxy-3′-methylglutaryl-coenzyme A reductase, MVA kinase, farnes...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Laezza, C, D'Alessandro, A, Di Croce, L, Picardi, P, Ciaglia, E, Pisanti, S, Malfitano, A M, Comegna, M, Faraonio, R, Gazzerro, P, Bifulco, M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632304/
https://ncbi.nlm.nih.gov/pubmed/26469958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.279
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