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Interaction of cepharanthine with immobilized heat shock protein 90α (Hsp90α) and screening of Hsp90α inhibitors

Heat shock protein 90α (Hsp90α) immobilized on aminopropyl silica gels was prepared via the N- or C-terminal, which was termed Hsp90α-NT or Hsp90α-CT, respectively. Binding interactions of biscoclaurine alkaloids (cepharanthine (CEP), berbamine (BBM), isotetrandrine (ITD), and cycleanine (CCN)) with...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Anal Biochem
Prif Awduron: Haginaka, Jun, Kitabatake, Tomoko, Hirose, Iyo, Matsunaga, Hisami, Matsunaga, Ruin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632246/
https://ncbi.nlm.nih.gov/pubmed/23219559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2012.11.010
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