Heat Shock Protein 90α (Hsp90α) Is Phosphorylated in Response to DNA Damage and Accumulates in Repair Foci

DNA damage triggers a complex signaling cascade involving a multitude of phosphorylation events. We found that the threonine 7 (Thr-7) residue of heat shock protein 90α (Hsp90α) was phosphorylated immediately after DNA damage. The phosphorylated Hsp90α then accumulated at sites of DNA double strand...

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Bibliographische Detailangaben
Hauptverfasser: Quanz, Maria, Herbette, Aurélie, Sayarath, Mano, de Koning, Leanne, Dubois, Thierry, Sun, Jian-Sheng, Dutreix, Marie
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
DNA and Chromosomes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308794/
https://ncbi.nlm.nih.gov/pubmed/22270370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.320887
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