Heterozygous disruption of activin receptor-like kinase 1 is associated with increased arterial pressure in mice

The activin receptor-like kinase 1 (ALK-1) is a type I cell-surface receptor for the transforming growth factor-β (TGF-β) family of proteins. Hypertension is related to TGF-β1, because increased TGF-β1 expression is correlated with an elevation in arterial pressure (AP) and TGF-β expression is upreg...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Dis Model Mech
Main Authors: González-Núñez, María, Riolobos, Adela S., Castellano, Orlando, Fuentes-Calvo, Isabel, de los Ángeles Sevilla, María, Oujo, Bárbara, Pericacho, Miguel, Cruz-Gonzalez, Ignacio, Pérez-Barriocanal, Fernando, ten Dijke, Peter, López-Novoa, Jose M.
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631783/
https://ncbi.nlm.nih.gov/pubmed/26398936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.019695
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