Inhibin α-Subunit N Terminus Interacts with Activin Type IB Receptor to Disrupt Activin Signaling

Inhibin is a heterodimeric peptide hormone produced in the ovary that antagonizes activin signaling and FSH synthesis in the pituitary. The inhibin β-subunit interacts with the activin type II receptor (ActRII) to functionally antagonize activin. The inhibin α-subunit mature domain (N terminus) aros...

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Autores principales: Zhu, Jie, Lin, S. Jack, Zou, Chao, Makanji, Yogeshwar, Jardetzky, Theodore S., Woodruff, Teresa K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318740/
https://ncbi.nlm.nih.gov/pubmed/22267736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.293381
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