The PKC-NFκB Signaling Pathway Induces APOBEC3B Expression in Multiple Human Cancers

Overexpression of the antiviral DNA cytosine deaminase APOBEC3B has been linked to somatic mutagenesis in many cancers. HPV infection accounts for APOBEC3B upregulation in cervical and head/neck cancers, but the mechanisms underlying non-viral malignancies are unclear. In this study, we investigated...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Res
Prif Awduron: Leonard, Brandon, McCann, Jennifer L., Starrett, Gabriel J., Kosyakovsky, Leah, Luengas, Elizabeth M., Molan, Amy M., Burns, Michael B., McDougle, Rebecca M., Parker, Peter J., Brown, William L., Harris, Reuben S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631676/
https://ncbi.nlm.nih.gov/pubmed/26420215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2171-T
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