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Crystallization and biochemical characterization of the human spliceosomal Aar2–Prp8(RNaseH) complex
In eukaryotes, the removal of nuclear noncoding sequences (pre-mRNA splicing) is catalyzed by the spliceosome, which consists of five ribonucleoprotein particles (U1, U2, U4, U5 and U6 snRNPs, each with a respective snRNA) and a plethora of protein factors that aid spliceosomal maturation, assembly,...
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| Publicado en: | Acta Crystallogr F Struct Biol Commun |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
International Union of Crystallography
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4631593/ https://ncbi.nlm.nih.gov/pubmed/26527271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15019202 |
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