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Crystallization and biochemical characterization of the human spliceosomal Aar2–Prp8(RNaseH) complex

In eukaryotes, the removal of nuclear noncoding sequences (pre-mRNA splicing) is catalyzed by the spliceosome, which consists of five ribonucleoprotein particles (U1, U2, U4, U5 and U6 snRNPs, each with a respective snRNA) and a plethora of protein factors that aid spliceosomal maturation, assembly,...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Main Authors: Santos, Karine, Preussner, Marco, Heroven, Anna Christina, Weber, Gert
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631593/
https://ncbi.nlm.nih.gov/pubmed/26527271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15019202
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