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The HoxC4 Homeodomain Protein Mediates Activation of the Immunoglobulin Heavy Chain 3′ hs1,2 Enhancer in Human B Cells: RELEVANCE TO CLASS SWITCH DNA RECOMBINATION()
The immunoglobulin heavy chain (IgH) 3′ regulatory region modulates IgH locus transcription, upon induction by specific trans-acting factors, and plays a significant role in class switch DNA recombination (CSR) and, perhaps, somatic hypermutation (SHM). CSR and SHM are central to the maturation of t...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4631311/ https://ncbi.nlm.nih.gov/pubmed/15252056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M407496200 |
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