Population pharmacokinetics of midazolam and its metabolites in overweight and obese adolescents

AIM: In view of the increasing prevalence of obesity in adolescents, the aim of this study was to determine the pharmacokinetics of the CYP3A substrate midazolam and its metabolites in overweight and obese adolescents. METHODS: Overweight (BMI for age ≥ 85(th) percentile) and obese (BMI for age ≥ 95...

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Detaylı Bibliyografya
Yayımlandı:Br J Clin Pharmacol
Asıl Yazarlar: van Rongen, Anne, Vaughns, Janelle D, Moorthy, Ganesh S, Barrett, Jeffrey S, Knibbe, Catherijne A J, van den Anker, Johannes N
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley & Sons, Ltd 2015
Konular:
Paediatric Clinical Pharmacology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631191/
https://ncbi.nlm.nih.gov/pubmed/26044579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12693
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