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V(H) and Vκ Segment Structure of Anti-Insulin IgG Autoantibodies in Patients with Insulin-Dependent Diabetes Mellitus: Evidence for Somatic Selection()
In some patients with insulin-dependent (type I) diabetes mellitus (IDDM), autoantibodies to insulin are present at diagnosis. After initiation of the treatment with not only animal but also human insulin, anti-insulin, mainly IgG, autoantibodies become a major component of the autoimmune response i...
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Publicado no: | J Immunol |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
1994
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4631048/ https://ncbi.nlm.nih.gov/pubmed/8301143 |
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